BDBM50309885 2-(6-(Pyrimidine-5-yl)oxazolo[4,5-b]pyridin-2-yl)-2,5-diazabicyclo[3.2.2]nonane::CHEMBL605955

SMILES: C1CN2CCC1N(CC2)c1nc2ncc(cc2o1)-c1cncnc1

InChI Key: InChIKey=UHVCBLPINYVBIX-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309885   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50309885 (2-(6-(Pyrimidine-5-yl)oxazolo[4,5-b]pyridin-2-yl)-...) Show SMILES C1CN2CCC1N(CC2)c1nc2ncc(cc2o1)-c1cncnc1 |TLB:9:6:0.1:4.3,(2.08,-1.36,;1.46,-2.5,;1.54,-4.2,;.55,-4.91,;.85,-3.47,;2.14,-2.77,;3.55,-3.39,;3.91,-4.86,;2.91,-4.14,;4.88,-2.62,;6.37,-3.03,;7.22,-1.75,;8.75,-1.51,;9.31,-.07,;8.33,1.13,;6.81,.89,;6.26,-.54,;4.82,-1.09,;8.81,2.61,;10.33,2.93,;10.82,4.41,;9.78,5.56,;8.25,5.24,;7.77,3.76,)| Show InChI InChI=1S/C17H18N6O/c1-3-22-4-2-14(1)23(6-5-22)17-21-16-15(24-17)7-12(10-20-16)13-8-18-11-19-9-13/h7-11,14H,1-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
5-HT3A Serotonin Receptor (Mus musculus (house mouse))	BDBM50309885 (2-(6-(Pyrimidine-5-yl)oxazolo[4,5-b]pyridin-2-yl)-...) Show SMILES C1CN2CCC1N(CC2)c1nc2ncc(cc2o1)-c1cncnc1 |TLB:9:6:0.1:4.3,(2.08,-1.36,;1.46,-2.5,;1.54,-4.2,;.55,-4.91,;.85,-3.47,;2.14,-2.77,;3.55,-3.39,;3.91,-4.86,;2.91,-4.14,;4.88,-2.62,;6.37,-3.03,;7.22,-1.75,;8.75,-1.51,;9.31,-.07,;8.33,1.13,;6.81,.89,;6.26,-.54,;4.82,-1.09,;8.81,2.61,;10.33,2.93,;10.82,4.41,;9.78,5.56,;8.25,5.24,;7.77,3.76,)| Show InChI InChI=1S/C17H18N6O/c1-3-22-4-2-14(1)23(6-5-22)17-21-16-15(24-17)7-12(10-20-16)13-8-18-11-19-9-13/h7-11,14H,1-6H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>7.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair