BDBM50309896 2-(5-(Piperidin-1-yl)oxazolo[4,5-b]pyridin-2-yl)-2,5-diazabicyclo-[3.2.2]nonane::CHEMBL599590

SMILES: C1CCN(CC1)c1ccc2oc(nc2n1)N1CCN2CCC1CC2

InChI Key: InChIKey=HBDDFXLYKUDJNH-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309896   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor (Rattus norvegicus (Rat))	BDBM50309896 (2-(5-(Piperidin-1-yl)oxazolo[4,5-b]pyridin-2-yl)-2...) Show SMILES C1CCN(CC1)c1ccc2oc(nc2n1)N1CCN2CCC1CC2 |TLB:11:15:20.19:22.23,(5.16,-33.93,;4.36,-35.26,;2.82,-35.24,;2.07,-33.89,;2.85,-32.56,;4.4,-32.58,;.53,-33.87,;-.35,-32.59,;-1.89,-32.71,;-2.56,-34.09,;-4.03,-34.52,;-4.1,-36.05,;-2.64,-36.58,;-1.69,-35.37,;-.15,-35.26,;-5.48,-36.72,;-5.23,-38.21,;-6.18,-37.41,;-7.55,-37.37,;-7.49,-35.67,;-6.79,-34.58,;-6.84,-35.99,;-8.18,-36.59,;-8.6,-38,)| Show InChI InChI=1S/C18H25N5O/c1-2-8-22(9-3-1)16-5-4-15-17(19-16)20-18(24-15)23-13-12-21-10-6-14(23)7-11-21/h4-5,14H,1-3,6-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	67.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
5-HT3A Serotonin Receptor (Mus musculus (house mouse))	BDBM50309896 (2-(5-(Piperidin-1-yl)oxazolo[4,5-b]pyridin-2-yl)-2...) Show SMILES C1CCN(CC1)c1ccc2oc(nc2n1)N1CCN2CCC1CC2 |TLB:11:15:20.19:22.23,(5.16,-33.93,;4.36,-35.26,;2.82,-35.24,;2.07,-33.89,;2.85,-32.56,;4.4,-32.58,;.53,-33.87,;-.35,-32.59,;-1.89,-32.71,;-2.56,-34.09,;-4.03,-34.52,;-4.1,-36.05,;-2.64,-36.58,;-1.69,-35.37,;-.15,-35.26,;-5.48,-36.72,;-5.23,-38.21,;-6.18,-37.41,;-7.55,-37.37,;-7.49,-35.67,;-6.79,-34.58,;-6.84,-35.99,;-8.18,-36.59,;-8.6,-38,)| Show InChI InChI=1S/C18H25N5O/c1-2-8-22(9-3-1)16-5-4-15-17(19-16)20-18(24-15)23-13-12-21-10-6-14(23)7-11-21/h4-5,14H,1-3,6-13H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair