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BDBM50309984 4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chlorophenyl)-N'-(1-(4-chlorophenyl)cyclopropanecarbonyl)-1-(2,4-dichlorophenyl)-1H-pyrazole-3-carbohydrazide::CHEMBL589446

SMILES: Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NNC(=O)C1(CC1)c1ccc(Cl)cc1

InChI Key: InChIKey=AXWUMKBQZZWDTH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50309984   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309984
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chloropheny...)
Show SMILES Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NNC(=O)C1(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C29H21Cl4N7O2/c30-19-5-1-17(2-6-19)26-22(14-39-16-34-15-35-39)25(38-40(26)24-10-9-21(32)13-23(24)33)27(41)36-37-28(42)29(11-12-29)18-3-7-20(31)8-4-18/h1-10,13,15-16H,11-12,14H2,(H,36,41)(H,37,42)
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 44.5n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair