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BDBM50310024 (4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-1H-pyrazol-3-yl)(4-(pyrimidin-2-yl)piperazin-1-yl)methanone::CHEMBL597832

SMILES: Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)c1ncccn1

InChI Key: InChIKey=XSWYXYFJTWIMAJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310024   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310024
PNG
((4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chlorophen...)
Show SMILES Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)c1ncccn1
Show InChI InChI=1S/C27H22Cl3N9O/c28-19-4-2-18(3-5-19)25-21(15-38-17-31-16-34-38)24(35-39(25)23-7-6-20(29)14-22(23)30)26(40)36-10-12-37(13-11-36)27-32-8-1-9-33-27/h1-9,14,16-17H,10-13,15H2
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 56n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair