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BDBM50310037 4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-1-(2-chlorophenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide::CHEMBL605759

SMILES: Clc1ccccc1-n1nc(C(=O)N2CCCCC2)c(Cn2cncn2)c1-c1ccc(Br)cc1

InChI Key: InChIKey=KTVURJRULBQROW-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310037   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310037
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Clc1ccccc1-n1nc(C(=O)N2CCCCC2)c(Cn2cncn2)c1-c1ccc(Br)cc1
Show InChI InChI=1S/C24H22BrClN6O/c25-18-10-8-17(9-11-18)23-19(14-31-16-27-15-28-31)22(24(33)30-12-4-1-5-13-30)29-32(23)21-7-3-2-6-20(21)26/h2-3,6-11,15-16H,1,4-5,12-14H2
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.23n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair