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BDBM50310043 4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-N-((1R,2S)-2-methylcyclohexyl)-1H-pyrazole-3-carboxamide::CHEMBL604924

SMILES: C[C@@H]1CCCC[C@@H]1NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=XNTZIHJNBFBASY-ZHRRBRCNSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310043   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor


(Rattus norvegicus (rat))
BDBM50310043
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chloropheny...)
Show SMILES C[C@@H]1CCCC[C@@H]1NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C26H25Cl3N6O/c1-16-4-2-3-5-22(16)32-26(36)24-20(13-34-15-30-14-31-34)25(17-6-8-18(27)9-7-17)35(33-24)23-11-10-19(28)12-21(23)29/h6-12,14-16,22H,2-5,13H2,1H3,(H,32,36)/t16-,22+/m1/s1
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Similars

Article
PubMed
n/an/a 18.3n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)

More data for this
Ligand-Target Pair