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BDBM50310052 4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl)-N-cyclohexyl-1-(2,4-dichlorophenyl)-1H-pyrazole-3-carboxamide::CHEMBL597731

SMILES: Clc1ccc(c(Cl)c1)-n1nc(C(=O)NC2CCCCC2)c(Cn2cncn2)c1-c1ccc(Br)cc1

InChI Key: InChIKey=UBMLADYSQNDCAC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310052   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310052
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NC2CCCCC2)c(Cn2cncn2)c1-c1ccc(Br)cc1
Show InChI InChI=1S/C25H23BrCl2N6O/c26-17-8-6-16(7-9-17)24-20(13-33-15-29-14-30-33)23(25(35)31-19-4-2-1-3-5-19)32-34(24)22-11-10-18(27)12-21(22)28/h6-12,14-15,19H,1-5,13H2,(H,31,35)
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.38n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair