BDBM50310164 (1R,2R)-2-(4-Chlorobenzylamino)methyl-1-(5(4)-methyl-1H-imidazol-4(5)-yl)cyclopropane::CHEMBL610492

SMILES: Cc1nc[nH]c1[C@@H]1C[C@H]1CNCc1ccc(Cl)cc1

InChI Key: InChIKey=HEAXBETWXPYFMF-GXTWGEPZSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50310164   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50310164 ((1R,2R)-2-(4-Chlorobenzylamino)methyl-1-(5(4)-meth...) Show SMILES Cc1nc[nH]c1[C@@H]1C[C@H]1CNCc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H18ClN3/c1-10-15(19-9-18-10)14-6-12(14)8-17-7-11-2-4-13(16)5-3-11/h2-5,9,12,14,17H,6-8H2,1H3,(H,18,19)/t12-,14+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor				Bioorg Med Chem 18: 1076-82 (2010) Article DOI: 10.1016/j.bmc.2009.12.046 BindingDB Entry DOI: 10.7270/Q21V5F35
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50310164 ((1R,2R)-2-(4-Chlorobenzylamino)methyl-1-(5(4)-meth...) Show SMILES Cc1nc[nH]c1[C@@H]1C[C@H]1CNCc1ccc(Cl)cc1 |r| Show InChI InChI=1S/C15H18ClN3/c1-10-15(19-9-18-10)14-6-12(14)8-17-7-11-2-4-13(16)5-3-11/h2-5,9,12,14,17H,6-8H2,1H3,(H,18,19)/t12-,14+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Displacement of [3H]Nalpha-methylahistamine from human histamine H3 receptor				Bioorg Med Chem 18: 1076-82 (2010) Article DOI: 10.1016/j.bmc.2009.12.046 BindingDB Entry DOI: 10.7270/Q21V5F35
					More data for this Ligand-Target Pair