BDBM50310213 7-(3'-Cyclopentyloxy-4'-methoxyphenyl)-2-(2,5-dichlorophenyl)pyrazolo[1,5-a]pyrimidine::CHEMBL606214

SMILES: COc1ccc(cc1OC1CCCC1)-c1ccnc2cc(nn12)-c1cc(Cl)ccc1Cl

InChI Key: InChIKey=GGGNXORJESILCC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310213   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50310213 (7-(3'-Cyclopentyloxy-4'-methoxyphenyl)-2-(2,5-dich...) Show SMILES COc1ccc(cc1OC1CCCC1)-c1ccnc2cc(nn12)-c1cc(Cl)ccc1Cl Show InChI InChI=1S/C24H21Cl2N3O2/c1-30-22-9-6-15(12-23(22)31-17-4-2-3-5-17)21-10-11-27-24-14-20(28-29(21)24)18-13-16(25)7-8-19(18)26/h6-14,17H,2-5H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of human PDE4D				Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S
					More data for this Ligand-Target Pair