BDBM50310238 3-[7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphenyl)-pyrazolo[1,5-a]pyrimidin-2-yl]-N-ethylbenzamide::CHEMBL598907

SMILES: CCNC(=O)c1cccc(c1)-c1cc2nccc(-c3ccc(OC(F)F)c(OCC4CC4)c3)n2n1

InChI Key: InChIKey=OASNBGXSRAIITI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310238   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50310238 (3-[7-(3'-Cyclopropylmethoxy-4'-difluoromethoxyphen...) Show SMILES CCNC(=O)c1cccc(c1)-c1cc2nccc(-c3ccc(OC(F)F)c(OCC4CC4)c3)n2n1 Show InChI InChI=1S/C26H24F2N4O3/c1-2-29-25(33)19-5-3-4-17(12-19)20-14-24-30-11-10-21(32(24)31-20)18-8-9-22(35-26(27)28)23(13-18)34-15-16-6-7-16/h3-5,8-14,16,26H,2,6-7,15H2,1H3,(H,29,33)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of human PDE4D				Bioorg Med Chem Lett 20: 922-6 (2010) Article DOI: 10.1016/j.bmcl.2009.12.070 BindingDB Entry DOI: 10.7270/Q2SF2W9S
					More data for this Ligand-Target Pair