BDBM50310312 CHEMBL597509::N,N'-bis(3,4-dihydroxybenzenesulfonyl)piperazine

SMILES: Oc1ccc(cc1O)S(=O)(=O)N1CCN(CC1)S(=O)(=O)c1ccc(O)c(O)c1

InChI Key: InChIKey=DNZGHSXUCVEJDF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50310312   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasminogen activator inhibitor-1 (Homo sapiens (Human))	BDBM50310312 (CHEMBL597509 | N,N'-bis(3,4-dihydroxybenzenesulfon...) Show SMILES Oc1ccc(cc1O)S(=O)(=O)N1CCN(CC1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H18N2O8S2/c19-13-3-1-11(9-15(13)21)27(23,24)17-5-7-18(8-6-17)28(25,26)12-2-4-14(20)16(22)10-12/h1-4,9-10,19-22H,5-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eastern Michigan University Curated by ChEMBL					Assay Description Inhibition of human recombinant PAI1 assessed as rate of AMC release after 30 mins				Bioorg Med Chem Lett 20: 966-70 (2010) Article DOI: 10.1016/j.bmcl.2009.12.051 BindingDB Entry DOI: 10.7270/Q24M94P3
					More data for this Ligand-Target Pair
Coagulation factor X/antithrombin III (Homo sapiens (Human))	BDBM50310312 (CHEMBL597509 | N,N'-bis(3,4-dihydroxybenzenesulfon...) Show SMILES Oc1ccc(cc1O)S(=O)(=O)N1CCN(CC1)S(=O)(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C16H18N2O8S2/c19-13-3-1-11(9-15(13)21)27(23,24)17-5-7-18(8-6-17)28(25,26)12-2-4-14(20)16(22)10-12/h1-4,9-10,19-22H,5-8H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Eastern Michigan University Curated by ChEMBL					Assay Description Inhibition of antithrombin-3 assessed as residual alpha-thrombin activity				Bioorg Med Chem Lett 20: 966-70 (2010) Article DOI: 10.1016/j.bmcl.2009.12.051 BindingDB Entry DOI: 10.7270/Q24M94P3
					More data for this Ligand-Target Pair