BDBM50310610 CHEMBL1079150::N-(4-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)phenyl)benzo[d]oxazol-2-amine

SMILES: C(Cc1ccc(Nc2nc3ccccc3o2)cc1)Nc1ncnc2ccsc12

InChI Key: InChIKey=STXFSYACLJLVGM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310610   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM50310610 (CHEMBL1079150 | N-(4-(2-(thieno[3,2-d]pyrimidin-4-...) Show SMILES C(Cc1ccc(Nc2nc3ccccc3o2)cc1)Nc1ncnc2ccsc12 Show InChI InChI=1S/C21H17N5OS/c1-2-4-18-16(3-1)26-21(27-18)25-15-7-5-14(6-8-15)9-11-22-20-19-17(10-12-28-19)23-13-24-20/h1-8,10,12-13H,9,11H2,(H,25,26)(H,22,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B after 60 mins				Bioorg Med Chem Lett 19: 5158-61 (2009) Article DOI: 10.1016/j.bmcl.2009.07.016 BindingDB Entry DOI: 10.7270/Q2T72HK2
					More data for this Ligand-Target Pair