BDBM50310612 CHEMBL1079051::N-(4-(3H-imidazo[4,5-c]pyridin-2-ylamino)phenethyl)thieno[3,2-d]pyrimidin-4-amine

SMILES: C(Cc1ccc(Nc2nc3ccncc3[nH]2)cc1)Nc1ncnc2ccsc12

InChI Key: InChIKey=IOYLPOUSBKYTPC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310612   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM50310612 (CHEMBL1079051 | N-(4-(3H-imidazo[4,5-c]pyridin-2-y...) Show SMILES C(Cc1ccc(Nc2nc3ccncc3[nH]2)cc1)Nc1ncnc2ccsc12 Show InChI InChI=1S/C20H17N7S/c1-3-14(25-20-26-15-6-8-21-11-17(15)27-20)4-2-13(1)5-9-22-19-18-16(7-10-28-18)23-12-24-19/h1-4,6-8,10-12H,5,9H2,(H,22,23,24)(H2,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B after 60 mins				Bioorg Med Chem Lett 19: 5158-61 (2009) Article DOI: 10.1016/j.bmcl.2009.07.016 BindingDB Entry DOI: 10.7270/Q2T72HK2
					More data for this Ligand-Target Pair