BDBM50310619 CHEMBL1078827::N-(2-(2-(1H-benzo[d]imidazol-2-ylamino)thiazol-5-yl)ethyl)thieno[3,2-d]pyrimidin-4-amine

SMILES: C(Cc1cnc(Nc2nc3ccccc3[nH]2)s1)Nc1ncnc2ccsc12

InChI Key: InChIKey=CPSQBCZJMZEPOE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50310619   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50310619 (CHEMBL1078827 | N-(2-(2-(1H-benzo[d]imidazol-2-yla...) Show SMILES C(Cc1cnc(Nc2nc3ccccc3[nH]2)s1)Nc1ncnc2ccsc12 Show InChI InChI=1S/C18H15N7S2/c1-2-4-13-12(3-1)23-17(24-13)25-18-20-9-11(27-18)5-7-19-16-15-14(6-8-26-15)21-10-22-16/h1-4,6,8-10H,5,7H2,(H,19,21,22)(H2,20,23,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora A after 60 mins				Bioorg Med Chem Lett 19: 5158-61 (2009) Article DOI: 10.1016/j.bmcl.2009.07.016 BindingDB Entry DOI: 10.7270/Q2T72HK2
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50310619 (CHEMBL1078827 | N-(2-(2-(1H-benzo[d]imidazol-2-yla...) Show SMILES C(Cc1cnc(Nc2nc3ccccc3[nH]2)s1)Nc1ncnc2ccsc12 Show InChI InChI=1S/C18H15N7S2/c1-2-4-13-12(3-1)23-17(24-13)25-18-20-9-11(27-18)5-7-19-16-15-14(6-8-26-15)21-10-22-16/h1-4,6,8-10H,5,7H2,(H,19,21,22)(H2,20,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B after 60 mins				Bioorg Med Chem Lett 19: 5158-61 (2009) Article DOI: 10.1016/j.bmcl.2009.07.016 BindingDB Entry DOI: 10.7270/Q2T72HK2
					More data for this Ligand-Target Pair