BDBM50310625 CHEMBL1080080::N-(4-(4,5-dimethyl-1H-imidazol-2-ylamino)phenethyl)thieno[3,2-d]pyrimidin-4-amine

SMILES: Cc1nc(Nc2ccc(CCNc3ncnc4ccsc34)cc2)[nH]c1C

InChI Key: InChIKey=OPEMEJXYSKVLOB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310625   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM50310625 (CHEMBL1080080 | N-(4-(4,5-dimethyl-1H-imidazol-2-y...) Show SMILES Cc1nc(Nc2ccc(CCNc3ncnc4ccsc34)cc2)[nH]c1C Show InChI InChI=1S/C19H20N6S/c1-12-13(2)24-19(23-12)25-15-5-3-14(4-6-15)7-9-20-18-17-16(8-10-26-17)21-11-22-18/h3-6,8,10-11H,7,9H2,1-2H3,(H,20,21,22)(H2,23,24,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B after 60 mins				Bioorg Med Chem Lett 19: 5158-61 (2009) Article DOI: 10.1016/j.bmcl.2009.07.016 BindingDB Entry DOI: 10.7270/Q2T72HK2
					More data for this Ligand-Target Pair