BDBM50310627 CHEMBL1080981::N-(2-(2-(3-(trifluoromethyl)phenylamino)-1H-benzo[d]imidazol-6-yl)ethyl)thieno[3,2-d]pyrimidin-4-amine

SMILES: FC(F)(F)c1cccc(Nc2nc3ccc(CCNc4ncnc5ccsc45)cc3[nH]2)c1

InChI Key: InChIKey=AHPOODNBWXPMQB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310627   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM50310627 (CHEMBL1080981 | N-(2-(2-(3-(trifluoromethyl)phenyl...) Show SMILES FC(F)(F)c1cccc(Nc2nc3ccc(CCNc4ncnc5ccsc45)cc3[nH]2)c1 Show InChI InChI=1S/C22H17F3N6S/c23-22(24,25)14-2-1-3-15(11-14)29-21-30-16-5-4-13(10-18(16)31-21)6-8-26-20-19-17(7-9-32-19)27-12-28-20/h1-5,7,9-12H,6,8H2,(H,26,27,28)(H2,29,30,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sunesis Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B after 60 mins				Bioorg Med Chem Lett 19: 5158-61 (2009) Article DOI: 10.1016/j.bmcl.2009.07.016 BindingDB Entry DOI: 10.7270/Q2T72HK2
					More data for this Ligand-Target Pair