BDBM50310632 CHEMBL1081345::N-(4-(3-(5-tert-butylisoxazol-3-yl)ureido)phenyl)-2-naphthamide

SMILES: CC(C)(C)c1cc(NC(=O)Nc2ccc(NC(=O)c3ccc4ccccc4c3)cc2)no1

InChI Key: InChIKey=DXYXGWPMYTZPKE-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310632   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50310632 (CHEMBL1081345 | N-(4-(3-(5-tert-butylisoxazol-3-yl...) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(NC(=O)c3ccc4ccccc4c3)cc2)no1 Show InChI InChI=1S/C25H24N4O3/c1-25(2,3)21-15-22(29-32-21)28-24(31)27-20-12-10-19(11-13-20)26-23(30)18-9-8-16-6-4-5-7-17(16)14-18/h4-15H,1-3H3,(H,26,30)(H2,27,28,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Inc. Curated by ChEMBL					Assay Description Binding affinity to FLT3				Bioorg Med Chem Lett 19: 5182-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.024 BindingDB Entry DOI: 10.7270/Q2PG1RVB
					More data for this Ligand-Target Pair