BDBM50310638 CHEMBL1080063::N-(4-(3-(5-tert-butylisoxazol-3-yl)ureido)phenyl)-5-methylbenzo[b]thiophene-2-carboxamide

SMILES: Cc1ccc2sc(cc2c1)C(=O)Nc1ccc(NC(=O)Nc2cc(on2)C(C)(C)C)cc1

InChI Key: InChIKey=ROCCXTVQIHMEEO-UHFFFAOYSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310638   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50310638 (CHEMBL1080063 | N-(4-(3-(5-tert-butylisoxazol-3-yl...) Show SMILES Cc1ccc2sc(cc2c1)C(=O)Nc1ccc(NC(=O)Nc2cc(on2)C(C)(C)C)cc1 Show InChI InChI=1S/C24H24N4O3S/c1-14-5-10-18-15(11-14)12-19(32-18)22(29)25-16-6-8-17(9-7-16)26-23(30)27-21-13-20(31-28-21)24(2,3)4/h5-13H,1-4H3,(H,25,29)(H2,26,27,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	0.770	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Inc. Curated by ChEMBL					Assay Description Binding affinity to FLT3				Bioorg Med Chem Lett 19: 5182-5 (2009) Article DOI: 10.1016/j.bmcl.2009.07.024 BindingDB Entry DOI: 10.7270/Q2PG1RVB
					More data for this Ligand-Target Pair