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BDBM50310793 CHEMBL1079291::N-(4-chlorophenyl)-3-(3-hydroxypropyl)-3-phenylpiperidine-1-carboxamide

SMILES: OCCCC1(CCCN(C1)C(=O)Nc1ccc(Cl)cc1)c1ccccc1

InChI Key: InChIKey=YVZSCJHEMPRIEE-UHFFFAOYSA-N

Data: 5 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50310793
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50310793 (CHEMBL1079291 \| N-(4-chlorophenyl)-3-(3-hydroxypro...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human soluble epoxide hydrolase				Bioorg Med Chem Lett 19: 5314-20 (2009) Article DOI: 10.1016/j.bmcl.2009.07.138 BindingDB Entry DOI: 10.7270/Q2S75GFP
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Epoxide hydrolase 2 (Rattus norvegicus)	BDBM50310793 (CHEMBL1079291 \| N-(4-chlorophenyl)-3-(3-hydroxypro...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of rat soluble epoxide hydrolase				Bioorg Med Chem Lett 19: 5314-20 (2009) Article DOI: 10.1016/j.bmcl.2009.07.138 BindingDB Entry DOI: 10.7270/Q2S75GFP
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50310793 (CHEMBL1079291 \| N-(4-chlorophenyl)-3-(3-hydroxypro...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Nav1.5 channel				Bioorg Med Chem Lett 19: 5314-20 (2009) Article DOI: 10.1016/j.bmcl.2009.07.138 BindingDB Entry DOI: 10.7270/Q2S75GFP
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50310793 (CHEMBL1079291 \| N-(4-chlorophenyl)-3-(3-hydroxypro...) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of CYP2D6				Bioorg Med Chem Lett 19: 5314-20 (2009) Article DOI: 10.1016/j.bmcl.2009.07.138 BindingDB Entry DOI: 10.7270/Q2S75GFP
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Epoxide hydrolase 1 (Homo sapiens (Human))	BDBM50310793 (CHEMBL1079291 \| N-(4-chlorophenyl)-3-(3-hydroxypro...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human microsomal epoxide hydrolase				Bioorg Med Chem Lett 19: 5314-20 (2009) Article DOI: 10.1016/j.bmcl.2009.07.138 BindingDB Entry DOI: 10.7270/Q2S75GFP
Merck Research Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair