BDBM50310935 3-bromo-6-(cyclopropylmethyl)-10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,4]diazepine::CHEMBL1080398

SMILES: Cc1ncn-2c1Cn1nc(CC3CC3)nc1-c1cc(Br)ccc-21

InChI Key: InChIKey=LHDPGSHJSSZMRH-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50310935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-5/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50310935 (3-bromo-6-(cyclopropylmethyl)-10-methyl-9H-benzo[f...) Show SMILES Cc1ncn-2c1Cn1nc(CC3CC3)nc1-c1cc(Br)ccc-21 Show InChI InChI=1S/C17H16BrN5/c1-10-15-8-23-17(20-16(21-23)6-11-2-3-11)13-7-12(18)4-5-14(13)22(15)9-19-10/h4-5,7,9,11H,2-3,6,8H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptor				Bioorg Med Chem Lett 19: 5958-61 (2009) Article DOI: 10.1016/j.bmcl.2009.08.027 BindingDB Entry DOI: 10.7270/Q2R78FBR
					More data for this Ligand-Target Pair
GABA receptor alpha-3/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50310935 (3-bromo-6-(cyclopropylmethyl)-10-methyl-9H-benzo[f...) Show SMILES Cc1ncn-2c1Cn1nc(CC3CC3)nc1-c1cc(Br)ccc-21 Show InChI InChI=1S/C17H16BrN5/c1-10-15-8-23-17(20-16(21-23)6-11-2-3-11)13-7-12(18)4-5-14(13)22(15)9-19-10/h4-5,7,9,11H,2-3,6,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	407	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from GABAAalpha3beta3gamma2 receptor				Bioorg Med Chem Lett 19: 5958-61 (2009) Article DOI: 10.1016/j.bmcl.2009.08.027 BindingDB Entry DOI: 10.7270/Q2R78FBR
					More data for this Ligand-Target Pair
GABA receptor alpha-2/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50310935 (3-bromo-6-(cyclopropylmethyl)-10-methyl-9H-benzo[f...) Show SMILES Cc1ncn-2c1Cn1nc(CC3CC3)nc1-c1cc(Br)ccc-21 Show InChI InChI=1S/C17H16BrN5/c1-10-15-8-23-17(20-16(21-23)6-11-2-3-11)13-7-12(18)4-5-14(13)22(15)9-19-10/h4-5,7,9,11H,2-3,6,8H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	407	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from GABAAalpha2beta3gamma2 receptor				Bioorg Med Chem Lett 19: 5958-61 (2009) Article DOI: 10.1016/j.bmcl.2009.08.027 BindingDB Entry DOI: 10.7270/Q2R78FBR
					More data for this Ligand-Target Pair
GABA receptor alpha-1/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50310935 (3-bromo-6-(cyclopropylmethyl)-10-methyl-9H-benzo[f...) Show SMILES Cc1ncn-2c1Cn1nc(CC3CC3)nc1-c1cc(Br)ccc-21 Show InChI InChI=1S/C17H16BrN5/c1-10-15-8-23-17(20-16(21-23)6-11-2-3-11)13-7-12(18)4-5-14(13)22(15)9-19-10/h4-5,7,9,11H,2-3,6,8H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	538	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from GABAAalpha1beta3gamma2 receptor				Bioorg Med Chem Lett 19: 5958-61 (2009) Article DOI: 10.1016/j.bmcl.2009.08.027 BindingDB Entry DOI: 10.7270/Q2R78FBR
					More data for this Ligand-Target Pair