BDBM50310945 3-methyl-5-((10-methyl-9H-benzo[f]imidazo[1,5-a][1,2,4]triazolo[1,5-d][1,4]diazepin-6-yl)methyl)isoxazole::CHEMBL1077468

SMILES: Cc1cc(Cc2nc3-c4ccccc4-n4cnc(C)c4Cn3n2)on1

InChI Key: InChIKey=LJFDWOOLSVVMQI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50310945   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA receptor alpha-5/beta-3/gamma-2 subunit (Homo sapiens (Human))	BDBM50310945 (3-methyl-5-((10-methyl-9H-benzo[f]imidazo[1,5-a][1...) Show SMILES Cc1cc(Cc2nc3-c4ccccc4-n4cnc(C)c4Cn3n2)on1 Show InChI InChI=1S/C18H16N6O/c1-11-7-13(25-22-11)8-17-20-18-14-5-3-4-6-15(14)23-10-19-12(2)16(23)9-24(18)21-17/h3-7,10H,8-9H2,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
F. Hoffmann-La Roche Ltd Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from GABAAalpha5beta3gamma2 receptor				Bioorg Med Chem Lett 19: 5958-61 (2009) Article DOI: 10.1016/j.bmcl.2009.08.027 BindingDB Entry DOI: 10.7270/Q2R78FBR
					More data for this Ligand-Target Pair