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BDBM50310966 4-((3-bromo-4-(2,4-difluorobenzyloxy)-6-methyl-2-oxopyridin-1(2H)-yl)methyl)benzamide::CHEMBL1078859

SMILES: Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1Cc1ccc(cc1)C(N)=O

InChI Key: InChIKey=PHGFIDCHPGXZAU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50310966   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 9


(Homo sapiens (Human))
BDBM50310966
PNG
(4-((3-bromo-4-(2,4-difluorobenzyloxy)-6-methyl-2-o...)
Show SMILES Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1Cc1ccc(cc1)C(N)=O
Show InChI InChI=1S/C21H17BrF2N2O3/c1-12-8-18(29-11-15-6-7-16(23)9-17(15)24)19(22)21(28)26(12)10-13-2-4-14(5-3-13)20(25)27/h2-9H,10-11H2,1H3,(H2,25,27)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a>2.00E+5n/an/an/an/an/an/a



Pfizer Corporation

Curated by ChEMBL


Assay Description
Inhibition of JNK2


Bioorg Med Chem Lett 19: 5851-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.082
BindingDB Entry DOI: 10.7270/Q2HM59DG
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50310966
PNG
(4-((3-bromo-4-(2,4-difluorobenzyloxy)-6-methyl-2-o...)
Show SMILES Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1Cc1ccc(cc1)C(N)=O
Show InChI InChI=1S/C21H17BrF2N2O3/c1-12-8-18(29-11-15-6-7-16(23)9-17(15)24)19(22)21(28)26(12)10-13-2-4-14(5-3-13)20(25)27/h2-9H,10-11H2,1H3,(H2,25,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 22n/an/an/an/an/an/a



Pfizer Corporation

Curated by ChEMBL


Assay Description
Inhibition of p38alpha


Bioorg Med Chem Lett 19: 5851-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.08.082
BindingDB Entry DOI: 10.7270/Q2HM59DG
More data for this
Ligand-Target Pair