BDBM50310969 4-((3-chloro-4-(2,4-difluorobenzyloxy)-6-methyl-2-oxopyridin-1(2H)-yl)methyl)-N,N-dimethylbenzamide::CHEMBL1079110

SMILES: CN(C)C(=O)c1ccc(Cn2c(C)cc(OCc3ccc(F)cc3F)c(Cl)c2=O)cc1

InChI Key: InChIKey=SNHKGZCRUXCSTA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50310969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50310969 (4-((3-chloro-4-(2,4-difluorobenzyloxy)-6-methyl-2-...) Show SMILES CN(C)C(=O)c1ccc(Cn2c(C)cc(OCc3ccc(F)cc3F)c(Cl)c2=O)cc1 Show InChI InChI=1S/C23H21ClF2N2O3/c1-14-10-20(31-13-17-8-9-18(25)11-19(17)26)21(24)23(30)28(14)12-15-4-6-16(7-5-15)22(29)27(2)3/h4-11H,12-13H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Corporation Curated by ChEMBL					Assay Description Inhibition of JNK2				Bioorg Med Chem Lett 19: 5851-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.082 BindingDB Entry DOI: 10.7270/Q2HM59DG
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50310969 (4-((3-chloro-4-(2,4-difluorobenzyloxy)-6-methyl-2-...) Show SMILES CN(C)C(=O)c1ccc(Cn2c(C)cc(OCc3ccc(F)cc3F)c(Cl)c2=O)cc1 Show InChI InChI=1S/C23H21ClF2N2O3/c1-14-10-20(31-13-17-8-9-18(25)11-19(17)26)21(24)23(30)28(14)12-15-4-6-16(7-5-15)22(29)27(2)3/h4-11H,12-13H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Corporation Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 19: 5851-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.082 BindingDB Entry DOI: 10.7270/Q2HM59DG
					More data for this Ligand-Target Pair