BDBM50310984 3-bromo-4-(2,4-difluorobenzyloxy)-1-(4-((dimethylamino)methyl)benzyl)-6-methylpyridin-2(1H)-one::CHEMBL1078665::PHA-745052

SMILES: CN(C)Cc1ccc(Cn2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)cc1

InChI Key: InChIKey=DHXKHAXDIKGJKS-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50310984   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50310984 (3-bromo-4-(2,4-difluorobenzyloxy)-1-(4-((dimethyla...) Show SMILES CN(C)Cc1ccc(Cn2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)cc1 Show InChI InChI=1S/C23H23BrF2N2O2/c1-15-10-21(30-14-18-8-9-19(25)11-20(18)26)22(24)23(29)28(15)13-17-6-4-16(5-7-17)12-27(2)3/h4-11H,12-14H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of JNK2				Bioorg Med Chem Lett 20: 3146-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.088 BindingDB Entry DOI: 10.7270/Q20Z73F0
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 9 (Homo sapiens (Human))	BDBM50310984 (3-bromo-4-(2,4-difluorobenzyloxy)-1-(4-((dimethyla...) Show SMILES CN(C)Cc1ccc(Cn2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)cc1 Show InChI InChI=1S/C23H23BrF2N2O2/c1-15-10-21(30-14-18-8-9-19(25)11-20(18)26)22(24)23(29)28(15)13-17-6-4-16(5-7-17)12-27(2)3/h4-11H,12-14H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.71E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Corporation Curated by ChEMBL					Assay Description Inhibition of JNK2				Bioorg Med Chem Lett 19: 5851-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.082 BindingDB Entry DOI: 10.7270/Q2HM59DG
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50310984 (3-bromo-4-(2,4-difluorobenzyloxy)-1-(4-((dimethyla...) Show SMILES CN(C)Cc1ccc(Cn2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)cc1 Show InChI InChI=1S/C23H23BrF2N2O2/c1-15-10-21(30-14-18-8-9-19(25)11-20(18)26)22(24)23(29)28(15)13-17-6-4-16(5-7-17)12-27(2)3/h4-11H,12-14H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Corporation Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 19: 5851-6 (2009) Article DOI: 10.1016/j.bmcl.2009.08.082 BindingDB Entry DOI: 10.7270/Q2HM59DG
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50310984 (3-bromo-4-(2,4-difluorobenzyloxy)-1-(4-((dimethyla...) Show SMILES CN(C)Cc1ccc(Cn2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)cc1 Show InChI InChI=1S/C23H23BrF2N2O2/c1-15-10-21(30-14-18-8-9-19(25)11-20(18)26)22(24)23(29)28(15)13-17-6-4-16(5-7-17)12-27(2)3/h4-11H,12-14H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of p38alpha				Bioorg Med Chem Lett 20: 3146-9 (2010) Article DOI: 10.1016/j.bmcl.2010.03.088 BindingDB Entry DOI: 10.7270/Q20Z73F0
					More data for this Ligand-Target Pair