BDBM50311291 CHEMBL1078902::N-(2-(trifluoromethyl)phenyl)pyrazolo[1,5-a]pyridine-3-carboxamide

SMILES: FC(F)(F)c1ccccc1NC(=O)c1cnn2ccccc12

InChI Key: InChIKey=COHJHRCDXKZWIK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50311291   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 3 (Homo sapiens (Human))	BDBM50311291 (CHEMBL1078902 | N-(2-(trifluoromethyl)phenyl)pyraz...) Show SMILES FC(F)(F)c1ccccc1NC(=O)c1cnn2ccccc12 Show InChI InChI=1S/C15H10F3N3O/c16-15(17,18)11-5-1-2-6-12(11)20-14(22)10-9-19-21-8-4-3-7-13(10)21/h1-9H,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...				Bioorg Med Chem Lett 19: 6122-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.010 BindingDB Entry DOI: 10.7270/Q2T43T66
					More data for this Ligand-Target Pair