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SMILES: Cc1nc2ccc(cn2c1C(=O)Nc1ccccc1Cl)-c1ccccc1

InChI Key: InChIKey=WHMNCKBUNQISMC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50311315   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ephrin type-B receptor 3


(Homo sapiens (Human))		BDBM50311315
PNG
(CHEMBL1077738 | N-(2-chlorophenyl)-2-methyl-6-phen...)
Show SMILES Cc1nc2ccc(cn2c1C(=O)Nc1ccccc1Cl)-c1ccccc1
Show InChI InChI=1S/C21H16ClN3O/c1-14-20(21(26)24-18-10-6-5-9-17(18)22)25-13-16(11-12-19(25)23-14)15-7-3-2-4-8-15/h2-13H,1H3,(H,24,26)
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Article
PubMed
n/an/a 2.00E+4n/an/an/an/an/an/a



Harvard Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant EphB3 kinase-mediated BTK-peptide phosphorylation assessed as 33P incorporation after 30 mins by scintillation counti...

Bioorg Med Chem Lett 19: 6122-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.09.010
BindingDB Entry DOI: 10.7270/Q2T43T66
More data for this
Ligand-Target Pair