BDBM50311333 2-(1-(3,5-diethoxy-4-fluorobenzyl)piperidin-4-ylamino)benzo[d]oxazole-5-carboxamide::CHEMBL1080584
SMILES: CCOc1cc(CN2CCC(CC2)Nc2nc3cc(ccc3o2)C(N)=O)cc(OCC)c1F
InChI Key: InChIKey=FABHJNZNOHUOSL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Somatostatin receptor type 5 (Homo sapiens (Human)) | BDBM50311333 (2-(1-(3,5-diethoxy-4-fluorobenzyl)piperidin-4-ylam...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd Curated by ChEMBL | Assay Description Displacement of SST14 from human recombinant SST5 receptor expressed in CHO cells by radioligand binding assay | Bioorg Med Chem Lett 19: 6106-13 (2009) Article DOI: 10.1016/j.bmcl.2009.09.024 BindingDB Entry DOI: 10.7270/Q2PC32H9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 3 (Homo sapiens (Human)) | BDBM50311333 (2-(1-(3,5-diethoxy-4-fluorobenzyl)piperidin-4-ylam...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd Curated by ChEMBL | Assay Description Displacement of SST14 from human recombinant SST3 receptor | Bioorg Med Chem Lett 19: 6106-13 (2009) Article DOI: 10.1016/j.bmcl.2009.09.024 BindingDB Entry DOI: 10.7270/Q2PC32H9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50311333 (2-(1-(3,5-diethoxy-4-fluorobenzyl)piperidin-4-ylam...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd Curated by ChEMBL | Assay Description Displacement of SST14 from human recombinant SST2 receptor | Bioorg Med Chem Lett 19: 6106-13 (2009) Article DOI: 10.1016/j.bmcl.2009.09.024 BindingDB Entry DOI: 10.7270/Q2PC32H9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50311333 (2-(1-(3,5-diethoxy-4-fluorobenzyl)piperidin-4-ylam...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd Curated by ChEMBL | Assay Description Displacement of SST14 from human recombinant SST4 receptor | Bioorg Med Chem Lett 19: 6106-13 (2009) Article DOI: 10.1016/j.bmcl.2009.09.024 BindingDB Entry DOI: 10.7270/Q2PC32H9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50311333 (2-(1-(3,5-diethoxy-4-fluorobenzyl)piperidin-4-ylam...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd Curated by ChEMBL | Assay Description Inhibition of human ERG expressed in CHO cells by patch clamp technique | Bioorg Med Chem Lett 19: 6106-13 (2009) Article DOI: 10.1016/j.bmcl.2009.09.024 BindingDB Entry DOI: 10.7270/Q2PC32H9 | |||||||||||
More data for this Ligand-Target Pair |