null

SMILES: CNC(=O)CN1C(=O)OC2(CCN(CC2)C2CCC(CC2)C(C)C)c2ccccc12

InChI Key: InChIKey=XSGGRILSKJJOSZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50311474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50311474 (2-(1'-(4-isopropylcyclohexyl)-2-oxospiro[benzo[d][...) Show SMILES CNC(=O)CN1C(=O)OC2(CCN(CC2)C2CCC(CC2)C(C)C)c2ccccc12 |(5.88,4.99,;4.55,5.76,;3.21,4.99,;3.21,3.45,;1.88,5.76,;.55,5,;-.77,5.77,;-.77,7.31,;-2.1,5,;-2.11,3.48,;-3.45,4.25,;-4.77,3.48,;-4.78,1.93,;-3.44,1.16,;-2.1,1.94,;-6.11,1.16,;-7.45,1.94,;-8.78,1.18,;-8.79,-.37,;-7.46,-1.14,;-6.11,-.37,;-10.11,-1.13,;-11.45,-.36,;-10.11,-2.67,;-.78,2.71,;-.78,1.17,;.55,.4,;1.89,1.17,;1.88,2.72,;.54,3.48,)| Show InChI InChI=1S/C24H35N3O3/c1-17(2)18-8-10-19(11-9-18)26-14-12-24(13-15-26)20-6-4-5-7-21(20)27(23(29)30-24)16-22(28)25-3/h4-7,17-19H,8-16H2,1-3H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	106	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 6441-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.028 BindingDB Entry DOI: 10.7270/Q21J99W7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50311474 (2-(1'-(4-isopropylcyclohexyl)-2-oxospiro[benzo[d][...) Show SMILES CNC(=O)CN1C(=O)OC2(CCN(CC2)C2CCC(CC2)C(C)C)c2ccccc12 |(5.88,4.99,;4.55,5.76,;3.21,4.99,;3.21,3.45,;1.88,5.76,;.55,5,;-.77,5.77,;-.77,7.31,;-2.1,5,;-2.11,3.48,;-3.45,4.25,;-4.77,3.48,;-4.78,1.93,;-3.44,1.16,;-2.1,1.94,;-6.11,1.16,;-7.45,1.94,;-8.78,1.18,;-8.79,-.37,;-7.46,-1.14,;-6.11,-.37,;-10.11,-1.13,;-11.45,-.36,;-10.11,-2.67,;-.78,2.71,;-.78,1.17,;.55,.4,;1.89,1.17,;1.88,2.72,;.54,3.48,)| Show InChI InChI=1S/C24H35N3O3/c1-17(2)18-8-10-19(11-9-18)26-14-12-24(13-15-26)20-6-4-5-7-21(20)27(23(29)30-24)16-22(28)25-3/h4-7,17-19H,8-16H2,1-3H3,(H,25,28)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	108	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 19: 6441-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.028 BindingDB Entry DOI: 10.7270/Q21J99W7
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50311474 (2-(1'-(4-isopropylcyclohexyl)-2-oxospiro[benzo[d][...) Show SMILES CNC(=O)CN1C(=O)OC2(CCN(CC2)C2CCC(CC2)C(C)C)c2ccccc12 |(5.88,4.99,;4.55,5.76,;3.21,4.99,;3.21,3.45,;1.88,5.76,;.55,5,;-.77,5.77,;-.77,7.31,;-2.1,5,;-2.11,3.48,;-3.45,4.25,;-4.77,3.48,;-4.78,1.93,;-3.44,1.16,;-2.1,1.94,;-6.11,1.16,;-7.45,1.94,;-8.78,1.18,;-8.79,-.37,;-7.46,-1.14,;-6.11,-.37,;-10.11,-1.13,;-11.45,-.36,;-10.11,-2.67,;-.78,2.71,;-.78,1.17,;.55,.4,;1.89,1.17,;1.88,2.72,;.54,3.48,)| Show InChI InChI=1S/C24H35N3O3/c1-17(2)18-8-10-19(11-9-18)26-14-12-24(13-15-26)20-6-4-5-7-21(20)27(23(29)30-24)16-22(28)25-3/h4-7,17-19H,8-16H2,1-3H3,(H,25,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	448	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrs				Bioorg Med Chem Lett 19: 6441-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.028 BindingDB Entry DOI: 10.7270/Q21J99W7
					More data for this Ligand-Target Pair