null

SMILES: CNC(=O)CN1Cc2ccccc2N(C2CCN(Cc3ccc(C)c4ccccc34)CC2)C1=O

InChI Key: InChIKey=XAFOABBARHIQGF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311480   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50311480 (CHEMBL1079941 | N-methyl-2-(1-(1-((4-methylnaphtha...) Show SMILES CNC(=O)CN1Cc2ccccc2N(C2CCN(Cc3ccc(C)c4ccccc34)CC2)C1=O Show InChI InChI=1S/C28H32N4O2/c1-20-11-12-21(25-9-5-4-8-24(20)25)17-30-15-13-23(14-16-30)32-26-10-6-3-7-22(26)18-31(28(32)34)19-27(33)29-2/h3-12,23H,13-19H2,1-2H3,(H,29,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 19: 6441-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.028 BindingDB Entry DOI: 10.7270/Q21J99W7
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50311480 (CHEMBL1079941 | N-methyl-2-(1-(1-((4-methylnaphtha...) Show SMILES CNC(=O)CN1Cc2ccccc2N(C2CCN(Cc3ccc(C)c4ccccc34)CC2)C1=O Show InChI InChI=1S/C28H32N4O2/c1-20-11-12-21(25-9-5-4-8-24(20)25)17-30-15-13-23(14-16-30)32-26-10-6-3-7-22(26)18-31(28(32)34)19-27(33)29-2/h3-12,23H,13-19H2,1-2H3,(H,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 6441-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.028 BindingDB Entry DOI: 10.7270/Q21J99W7
					More data for this Ligand-Target Pair