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SMILES: CNC(=O)CN1Cc2ccccc2N(C2CCN(CC2)C2CCC(CC2)C(C)C)C1=O

InChI Key: InChIKey=VAFKCMXVSAMWJK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311490   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50311490 (2-(1-(1-(4-isopropylcyclohexyl)piperidin-4-yl)-2-o...) Show SMILES CNC(=O)CN1Cc2ccccc2N(C2CCN(CC2)C2CCC(CC2)C(C)C)C1=O |(14.47,8.87,;13.14,8.09,;13.14,6.55,;14.47,5.78,;11.81,5.78,;11.81,4.24,;13.13,3.47,;13.14,1.95,;14.48,1.2,;14.48,-.35,;13.14,-1.13,;11.81,-.35,;11.81,1.19,;10.49,1.94,;9.16,1.17,;7.82,1.94,;6.5,1.17,;6.49,-.37,;7.83,-1.14,;9.17,-.37,;5.16,-1.14,;3.82,-.36,;2.49,-1.13,;2.49,-2.67,;3.82,-3.44,;5.16,-2.67,;1.15,-3.43,;-.18,-2.66,;1.14,-4.97,;10.49,3.47,;9.15,4.24,)| Show InChI InChI=1S/C25H38N4O2/c1-18(2)19-8-10-21(11-9-19)27-14-12-22(13-15-27)29-23-7-5-4-6-20(23)16-28(25(29)31)17-24(30)26-3/h4-7,18-19,21-22H,8-17H2,1-3H3,(H,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 6441-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.028 BindingDB Entry DOI: 10.7270/Q21J99W7
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50311490 (2-(1-(1-(4-isopropylcyclohexyl)piperidin-4-yl)-2-o...) Show SMILES CNC(=O)CN1Cc2ccccc2N(C2CCN(CC2)C2CCC(CC2)C(C)C)C1=O |(14.47,8.87,;13.14,8.09,;13.14,6.55,;14.47,5.78,;11.81,5.78,;11.81,4.24,;13.13,3.47,;13.14,1.95,;14.48,1.2,;14.48,-.35,;13.14,-1.13,;11.81,-.35,;11.81,1.19,;10.49,1.94,;9.16,1.17,;7.82,1.94,;6.5,1.17,;6.49,-.37,;7.83,-1.14,;9.17,-.37,;5.16,-1.14,;3.82,-.36,;2.49,-1.13,;2.49,-2.67,;3.82,-3.44,;5.16,-2.67,;1.15,-3.43,;-.18,-2.66,;1.14,-4.97,;10.49,3.47,;9.15,4.24,)| Show InChI InChI=1S/C25H38N4O2/c1-18(2)19-8-10-21(11-9-19)27-14-12-22(13-15-27)29-23-7-5-4-6-20(23)16-28(25(29)31)17-24(30)26-3/h4-7,18-19,21-22H,8-17H2,1-3H3,(H,26,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cells				Bioorg Med Chem Lett 19: 6441-6 (2009) Article DOI: 10.1016/j.bmcl.2009.09.028 BindingDB Entry DOI: 10.7270/Q21J99W7
					More data for this Ligand-Target Pair