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SMILES: Cc1ccccc1Oc1cc(ncn1)N1CCC(CC1)Oc1ncc(F)c(N)n1

InChI Key: InChIKey=XDPUWAXHACXPOK-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311550   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Deoxycytidine kinase (Homo sapiens (Human))	BDBM50311550 (5-fluoro-2-(1-(6-(o-tolyloxy)pyrimidin-4-yl)piperi...) Show SMILES Cc1ccccc1Oc1cc(ncn1)N1CCC(CC1)Oc1ncc(F)c(N)n1 Show InChI InChI=1S/C20H21FN6O2/c1-13-4-2-3-5-16(13)29-18-10-17(24-12-25-18)27-8-6-14(7-9-27)28-20-23-11-15(21)19(22)26-20/h2-5,10-12,14H,6-9H2,1H3,(H2,22,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of human dCK				Bioorg Med Chem Lett 19: 6780-3 (2009) Article DOI: 10.1016/j.bmcl.2009.09.082 BindingDB Entry DOI: 10.7270/Q2HM58K9
					More data for this Ligand-Target Pair
Deoxycytidine kinase (Homo sapiens (Human))	BDBM50311550 (5-fluoro-2-(1-(6-(o-tolyloxy)pyrimidin-4-yl)piperi...) Show SMILES Cc1ccccc1Oc1cc(ncn1)N1CCC(CC1)Oc1ncc(F)c(N)n1 Show InChI InChI=1S/C20H21FN6O2/c1-13-4-2-3-5-16(13)29-18-10-17(24-12-25-18)27-8-6-14(7-9-27)28-20-23-11-15(21)19(22)26-20/h2-5,10-12,14H,6-9H2,1H3,(H2,22,23,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibition of dCK in human CCRF-CEM assessed as inhibition of Ara-C phosohorylation				Bioorg Med Chem Lett 19: 6780-3 (2009) Article DOI: 10.1016/j.bmcl.2009.09.082 BindingDB Entry DOI: 10.7270/Q2HM58K9
					More data for this Ligand-Target Pair