null

SMILES: Fc1cccc2OCCC(c12)n1c2nc(ncc2[nH]c1=O)-n1cnc2ccccc12

InChI Key: InChIKey=GWIYWVOOKZDFBH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311647   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50311647 ((+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(5-fluorochro...) Show SMILES Fc1cccc2OCCC(c12)n1c2nc(ncc2[nH]c1=O)-n1cnc2ccccc12 Show InChI InChI=1S/C21H15FN6O2/c22-12-4-3-7-17-18(12)16(8-9-30-17)28-19-14(25-21(28)29)10-23-20(26-19)27-11-24-13-5-1-2-6-15(13)27/h1-7,10-11,16H,8-9H2,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of human JAK2 (532-1132) by time resolved fluorescence assay				Bioorg Med Chem Lett 19: 6788-92 (2009) Article DOI: 10.1016/j.bmcl.2009.09.080 BindingDB Entry DOI: 10.7270/Q24B31G4
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50311647 ((+/-)-2-(1H-benzo[d]imidazol-1-yl)-9-(5-fluorochro...) Show SMILES Fc1cccc2OCCC(c12)n1c2nc(ncc2[nH]c1=O)-n1cnc2ccccc12 Show InChI InChI=1S/C21H15FN6O2/c22-12-4-3-7-17-18(12)16(8-9-30-17)28-19-14(25-21(28)29)10-23-20(26-19)27-11-24-13-5-1-2-6-15(13)27/h1-7,10-11,16H,8-9H2,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc Curated by ChEMBL					Assay Description Inhibition of human JAK3 (508-1124) by time resolved fluorescence assay				Bioorg Med Chem Lett 19: 6788-92 (2009) Article DOI: 10.1016/j.bmcl.2009.09.080 BindingDB Entry DOI: 10.7270/Q24B31G4
					More data for this Ligand-Target Pair