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SMILES: Nc1nccc(n1)-c1ccc2nc(sc2c1)C1COc2ccccc2C1

InChI Key: InChIKey=WWVZNRRDWRTNIA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311714   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50311714 (4-(2-(chroman-3-yl)benzo[d]thiazol-6-yl)pyrimidin-...) Show SMILES Nc1nccc(n1)-c1ccc2nc(sc2c1)C1COc2ccccc2C1 Show InChI InChI=1S/C20H16N4OS/c21-20-22-8-7-15(24-20)12-5-6-16-18(10-12)26-19(23-16)14-9-13-3-1-2-4-17(13)25-11-14/h1-8,10,14H,9,11H2,(H2,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute and Department of Molecular Therapeutics Curated by ChEMBL					Assay Description Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assay				Bioorg Med Chem Lett 19: 6686-90 (2009) Article DOI: 10.1016/j.bmcl.2009.09.115 BindingDB Entry DOI: 10.7270/Q2VX0GN0
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50311714 (4-(2-(chroman-3-yl)benzo[d]thiazol-6-yl)pyrimidin-...) Show SMILES Nc1nccc(n1)-c1ccc2nc(sc2c1)C1COc2ccccc2C1 Show InChI InChI=1S/C20H16N4OS/c21-20-22-8-7-15(24-20)12-5-6-16-18(10-12)26-19(23-16)14-9-13-3-1-2-4-17(13)25-11-14/h1-8,10,14H,9,11H2,(H2,21,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute and Department of Molecular Therapeutics Curated by ChEMBL					Assay Description Inhibition of ROCK2				Bioorg Med Chem Lett 19: 6686-90 (2009) Article DOI: 10.1016/j.bmcl.2009.09.115 BindingDB Entry DOI: 10.7270/Q2VX0GN0
					More data for this Ligand-Target Pair