BDBM50311945 4-(2-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)pyridin-3-yl)vinyl)benzenesulfonamide::CHEMBL1080801

SMILES: Cc1c(Nc2c(\C=C\c3ccc(cc3)S(N)(=O)=O)cncc2C#N)ccc2[nH]ccc12

InChI Key: InChIKey=BTFQHCKJTLZZRE-GORDUTHDSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311945   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50311945 (4-(2-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)pyrid...) Show SMILES Cc1c(Nc2c(\C=C\c3ccc(cc3)S(N)(=O)=O)cncc2C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C23H19N5O2S/c1-15-20-10-11-27-22(20)9-8-21(15)28-23-17(13-26-14-18(23)12-24)5-2-16-3-6-19(7-4-16)31(25,29)30/h2-11,13-14,27H,1H3,(H,26,28)(H2,25,29,30)/b5-2+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 19: 6575-7 (2009) Article DOI: 10.1016/j.bmcl.2009.10.031 BindingDB Entry DOI: 10.7270/Q2KD1Z1F
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50311945 (4-(2-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)pyrid...) Show SMILES Cc1c(Nc2c(\C=C\c3ccc(cc3)S(N)(=O)=O)cncc2C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C23H19N5O2S/c1-15-20-10-11-27-22(20)9-8-21(15)28-23-17(13-26-14-18(23)12-24)5-2-16-3-6-19(7-4-16)31(25,29)30/h2-11,13-14,27H,1H3,(H,26,28)(H2,25,29,30)/b5-2+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 19: 6575-7 (2009) Article DOI: 10.1016/j.bmcl.2009.10.031 BindingDB Entry DOI: 10.7270/Q2KD1Z1F
					More data for this Ligand-Target Pair