BDBM50311949 4-(2-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)pyridin-3-yl)vinyl)-N,N-diisopropylbenzenesulfonamide::CHEMBL1079376

SMILES: CC(C)N(C(C)C)S(=O)(=O)c1ccc(\C=C\c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)cc1

InChI Key: InChIKey=RLQRUADFPRQJMI-RMKNXTFCSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311949   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50311949 (4-(2-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)pyrid...) Show SMILES CC(C)N(C(C)C)S(=O)(=O)c1ccc(\C=C\c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)cc1 Show InChI InChI=1S/C29H31N5O2S/c1-19(2)34(20(3)4)37(35,36)25-10-7-22(8-11-25)6-9-23-17-31-18-24(16-30)29(23)33-27-12-13-28-26(21(27)5)14-15-32-28/h6-15,17-20,32H,1-5H3,(H,31,33)/b9-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 19: 6575-7 (2009) Article DOI: 10.1016/j.bmcl.2009.10.031 BindingDB Entry DOI: 10.7270/Q2KD1Z1F
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50311949 (4-(2-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)pyrid...) Show SMILES CC(C)N(C(C)C)S(=O)(=O)c1ccc(\C=C\c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)cc1 Show InChI InChI=1S/C29H31N5O2S/c1-19(2)34(20(3)4)37(35,36)25-10-7-22(8-11-25)6-9-23-17-31-18-24(16-30)29(23)33-27-12-13-28-26(21(27)5)14-15-32-28/h6-15,17-20,32H,1-5H3,(H,31,33)/b9-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 19: 6575-7 (2009) Article DOI: 10.1016/j.bmcl.2009.10.031 BindingDB Entry DOI: 10.7270/Q2KD1Z1F
					More data for this Ligand-Target Pair