BDBM50311951 4-(4-methyl-1H-indol-5-ylamino)-5-(3-(pyrrolidin-1-ylsulfonyl)styryl)nicotinonitrile::CHEMBL1081358

SMILES: Cc1c(Nc2c(\C=C\c3cccc(c3)S(=O)(=O)N3CCCC3)cncc2C#N)ccc2[nH]ccc12

InChI Key: InChIKey=XPKKUXKJOCVNEJ-BQYQJAHWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311951   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50311951 (4-(4-methyl-1H-indol-5-ylamino)-5-(3-(pyrrolidin-1...) Show SMILES Cc1c(Nc2c(\C=C\c3cccc(c3)S(=O)(=O)N3CCCC3)cncc2C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C27H25N5O2S/c1-19-24-11-12-30-26(24)10-9-25(19)31-27-21(17-29-18-22(27)16-28)8-7-20-5-4-6-23(15-20)35(33,34)32-13-2-3-14-32/h4-12,15,17-18,30H,2-3,13-14H2,1H3,(H,29,31)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 19: 6575-7 (2009) Article DOI: 10.1016/j.bmcl.2009.10.031 BindingDB Entry DOI: 10.7270/Q2KD1Z1F
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50311951 (4-(4-methyl-1H-indol-5-ylamino)-5-(3-(pyrrolidin-1...) Show SMILES Cc1c(Nc2c(\C=C\c3cccc(c3)S(=O)(=O)N3CCCC3)cncc2C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C27H25N5O2S/c1-19-24-11-12-30-26(24)10-9-25(19)31-27-21(17-29-18-22(27)16-28)8-7-20-5-4-6-23(15-20)35(33,34)32-13-2-3-14-32/h4-12,15,17-18,30H,2-3,13-14H2,1H3,(H,29,31)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 19: 6575-7 (2009) Article DOI: 10.1016/j.bmcl.2009.10.031 BindingDB Entry DOI: 10.7270/Q2KD1Z1F
					More data for this Ligand-Target Pair