BDBM50311957 6-methyl-4-(4-methyl-1H-indol-5-ylamino)-5-(4-(4-methylpiperazin-1-ylsulfonyl)styryl)nicotinonitrile::CHEMBL1079567

SMILES: CN1CCN(CC1)S(=O)(=O)c1ccc(\C=C\c2c(C)ncc(C#N)c2Nc2ccc3[nH]ccc3c2C)cc1

InChI Key: InChIKey=BOBBYUSYHORXQS-RMKNXTFCSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50311957   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C delta type (Homo sapiens (Human))	BDBM50311957 (6-methyl-4-(4-methyl-1H-indol-5-ylamino)-5-(4-(4-m...) Show SMILES CN1CCN(CC1)S(=O)(=O)c1ccc(\C=C\c2c(C)ncc(C#N)c2Nc2ccc3[nH]ccc3c2C)cc1 Show InChI InChI=1S/C29H30N6O2S/c1-20-25-12-13-31-28(25)11-10-27(20)33-29-23(18-30)19-32-21(2)26(29)9-6-22-4-7-24(8-5-22)38(36,37)35-16-14-34(3)15-17-35/h4-13,19,31H,14-17H2,1-3H3,(H,32,33)/b9-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 19: 6575-7 (2009) Article DOI: 10.1016/j.bmcl.2009.10.031 BindingDB Entry DOI: 10.7270/Q2KD1Z1F
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50311957 (6-methyl-4-(4-methyl-1H-indol-5-ylamino)-5-(4-(4-m...) Show SMILES CN1CCN(CC1)S(=O)(=O)c1ccc(\C=C\c2c(C)ncc(C#N)c2Nc2ccc3[nH]ccc3c2C)cc1 Show InChI InChI=1S/C29H30N6O2S/c1-20-25-12-13-31-28(25)11-10-27(20)33-29-23(18-30)19-32-21(2)26(29)9-6-22-4-7-24(8-5-22)38(36,37)35-16-14-34(3)15-17-35/h4-13,19,31H,14-17H2,1-3H3,(H,32,33)/b9-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 19: 6575-7 (2009) Article DOI: 10.1016/j.bmcl.2009.10.031 BindingDB Entry DOI: 10.7270/Q2KD1Z1F
					More data for this Ligand-Target Pair