BDBM50312042 (S)-N-(4-(4-phenyl-5,6-dihydro-4H-1,3-thiazin-2-ylamino)phenethyl)benzo[d]thiazol-2-amine::CHEMBL1080298
SMILES: C(Cc1ccc(cc1)N=C1N[C@@H](CCS1)c1ccccc1)Nc1nc2ccccc2s1
InChI Key: InChIKey=RGZGFOJOCZGGIT-NRFANRHFSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuropeptide Y receptor type 1 (Homo sapiens (Human)) | BDBM50312042 ((S)-N-(4-(4-phenyl-5,6-dihydro-4H-1,3-thiazin-2-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering Plough Research Institute Curated by ChEMBL | Assay Description Displacement of [125I]pig PPY from human NPY1 receptor expressed in CHOK1 cells by scintillation counting | Bioorg Med Chem Lett 19: 6801-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.048 BindingDB Entry DOI: 10.7270/Q2XP753Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptide Y receptor type 5 ( NPY Y5) (Homo sapiens (Human)) | BDBM50312042 ((S)-N-(4-(4-phenyl-5,6-dihydro-4H-1,3-thiazin-2-yl...) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering Plough Research Institute Curated by ChEMBL | Assay Description Displacement of [125I]pig PPY from human NPY5 receptor expressed in CHOK1 cells by scintillation counting | Bioorg Med Chem Lett 19: 6801-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.048 BindingDB Entry DOI: 10.7270/Q2XP753Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
PPYR1 (Homo sapiens (Human)) | BDBM50312042 ((S)-N-(4-(4-phenyl-5,6-dihydro-4H-1,3-thiazin-2-yl...) | Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering Plough Research Institute Curated by ChEMBL | Assay Description Displacement of [125I]human PP from human NPY4 receptor expressed in CHOK1 cells by scintillation counting | Bioorg Med Chem Lett 19: 6801-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.048 BindingDB Entry DOI: 10.7270/Q2XP753Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuropeptide Y receptor type 2 (Homo sapiens (Human)) | BDBM50312042 ((S)-N-(4-(4-phenyl-5,6-dihydro-4H-1,3-thiazin-2-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering Plough Research Institute Curated by ChEMBL | Assay Description Displacement of [125I]pig PPY from human NPY2 receptor expressed in CHOK1 cells by scintillation counting | Bioorg Med Chem Lett 19: 6801-5 (2009) Article DOI: 10.1016/j.bmcl.2009.09.048 BindingDB Entry DOI: 10.7270/Q2XP753Z | |||||||||||
More data for this Ligand-Target Pair |