BDBM50312150 1-(3-(8-(piperidin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea::CHEMBL1079960

SMILES: FC(F)(F)c1cccc(NC(=O)Nc2cccc(c2)-c2cn3ccnc3c(NCC3CCNCC3)n2)c1

InChI Key: InChIKey=OLQWTLPWZOPGNO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312150   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50312150 (1-(3-(8-(piperidin-4-ylmethylamino)imidazo[1,2-a]p...) Show SMILES FC(F)(F)c1cccc(NC(=O)Nc2cccc(c2)-c2cn3ccnc3c(NCC3CCNCC3)n2)c1 Show InChI InChI=1S/C26H26F3N7O/c27-26(28,29)19-4-2-6-21(14-19)34-25(37)33-20-5-1-3-18(13-20)22-16-36-12-11-31-24(36)23(35-22)32-15-17-7-9-30-10-8-17/h1-6,11-14,16-17,30H,7-10,15H2,(H,32,35)(H2,33,34,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
CGI Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of EphB4 autophosphorylation by cell based assay				Bioorg Med Chem Lett 19: 6991-5 (2009) Article DOI: 10.1016/j.bmcl.2009.10.037 BindingDB Entry DOI: 10.7270/Q2DR2VM3
					More data for this Ligand-Target Pair