Found 6 hits for monomerid = 50312155 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50312155
(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)Show SMILES COc1ccc(cc1NC(=O)Nc1cccc(c1)-c1cn2ccnc2c(NCc2ccncc2)n1)C(F)(F)F Show InChI InChI=1S/C27H22F3N7O2/c1-39-23-6-5-19(27(28,29)30)14-21(23)36-26(38)34-20-4-2-3-18(13-20)22-16-37-12-11-32-25(37)24(35-22)33-15-17-7-9-31-10-8-17/h2-14,16H,15H2,1H3,(H,33,35)(H2,34,36,38) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
CGI Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 after 1 hr |
Bioorg Med Chem Lett 19: 6991-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.037
BindingDB Entry DOI: 10.7270/Q2DR2VM3 |
More data for this
Ligand-Target Pair | |
Ephrin type-B receptor 4
(Homo sapiens (Human)) | BDBM50312155
(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)Show SMILES COc1ccc(cc1NC(=O)Nc1cccc(c1)-c1cn2ccnc2c(NCc2ccncc2)n1)C(F)(F)F Show InChI InChI=1S/C27H22F3N7O2/c1-39-23-6-5-19(27(28,29)30)14-21(23)36-26(38)34-20-4-2-3-18(13-20)22-16-37-12-11-32-25(37)24(35-22)33-15-17-7-9-31-10-8-17/h2-14,16H,15H2,1H3,(H,33,35)(H2,34,36,38) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
CGI Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of EphB4 after 1 hr |
Bioorg Med Chem Lett 19: 6991-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.037
BindingDB Entry DOI: 10.7270/Q2DR2VM3 |
More data for this
Ligand-Target Pair | |
Angiopoietin-1 receptor
(Homo sapiens (Human)) | BDBM50312155
(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)Show SMILES COc1ccc(cc1NC(=O)Nc1cccc(c1)-c1cn2ccnc2c(NCc2ccncc2)n1)C(F)(F)F Show InChI InChI=1S/C27H22F3N7O2/c1-39-23-6-5-19(27(28,29)30)14-21(23)36-26(38)34-20-4-2-3-18(13-20)22-16-37-12-11-32-25(37)24(35-22)33-15-17-7-9-31-10-8-17/h2-14,16H,15H2,1H3,(H,33,35)(H2,34,36,38) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
CGI Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of Tie2 autophosphorylation by cell based assay |
Bioorg Med Chem Lett 19: 6991-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.037
BindingDB Entry DOI: 10.7270/Q2DR2VM3 |
More data for this
Ligand-Target Pair | |
Ephrin type-B receptor 4
(Homo sapiens (Human)) | BDBM50312155
(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)Show SMILES COc1ccc(cc1NC(=O)Nc1cccc(c1)-c1cn2ccnc2c(NCc2ccncc2)n1)C(F)(F)F Show InChI InChI=1S/C27H22F3N7O2/c1-39-23-6-5-19(27(28,29)30)14-21(23)36-26(38)34-20-4-2-3-18(13-20)22-16-37-12-11-32-25(37)24(35-22)33-15-17-7-9-31-10-8-17/h2-14,16H,15H2,1H3,(H,33,35)(H2,34,36,38) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
CGI Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of EphB4 autophosphorylation by cell based assay |
Bioorg Med Chem Lett 19: 6991-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.037
BindingDB Entry DOI: 10.7270/Q2DR2VM3 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50312155
(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)Show SMILES COc1ccc(cc1NC(=O)Nc1cccc(c1)-c1cn2ccnc2c(NCc2ccncc2)n1)C(F)(F)F Show InChI InChI=1S/C27H22F3N7O2/c1-39-23-6-5-19(27(28,29)30)14-21(23)36-26(38)34-20-4-2-3-18(13-20)22-16-37-12-11-32-25(37)24(35-22)33-15-17-7-9-31-10-8-17/h2-14,16H,15H2,1H3,(H,33,35)(H2,34,36,38) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
CGI Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR2 autophosphorylation by cell based assay |
Bioorg Med Chem Lett 19: 6991-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.037
BindingDB Entry DOI: 10.7270/Q2DR2VM3 |
More data for this
Ligand-Target Pair | |
Angiopoietin-1 receptor
(Homo sapiens (Human)) | BDBM50312155
(1-(2-methoxy-5-(trifluoromethyl)phenyl)-3-(3-(8-(p...)Show SMILES COc1ccc(cc1NC(=O)Nc1cccc(c1)-c1cn2ccnc2c(NCc2ccncc2)n1)C(F)(F)F Show InChI InChI=1S/C27H22F3N7O2/c1-39-23-6-5-19(27(28,29)30)14-21(23)36-26(38)34-20-4-2-3-18(13-20)22-16-37-12-11-32-25(37)24(35-22)33-15-17-7-9-31-10-8-17/h2-14,16H,15H2,1H3,(H,33,35)(H2,34,36,38) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
CGI Pharmaceuticals, Inc.
Curated by ChEMBL
| Assay Description
Inhibition of Tie2 after 1 hr |
Bioorg Med Chem Lett 19: 6991-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.10.037
BindingDB Entry DOI: 10.7270/Q2DR2VM3 |
More data for this
Ligand-Target Pair | |
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