BDBM50312180 1-(3,5-dichlorophenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea::CHEMBL1081568

SMILES: Clc1cc(Cl)cc(NC(=O)Nc2cccc(c2)-c2cn3ccnc3c(NCc3ccncc3)n2)c1

InChI Key: InChIKey=GKDBVPFTJZEJII-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312180   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50312180 (1-(3,5-dichlorophenyl)-3-(3-(8-(pyridin-4-ylmethyl...) Show SMILES Clc1cc(Cl)cc(NC(=O)Nc2cccc(c2)-c2cn3ccnc3c(NCc3ccncc3)n2)c1 Show InChI InChI=1S/C25H19Cl2N7O/c26-18-11-19(27)13-21(12-18)32-25(35)31-20-3-1-2-17(10-20)22-15-34-9-8-29-24(34)23(33-22)30-14-16-4-6-28-7-5-16/h1-13,15H,14H2,(H,30,33)(H2,31,32,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
CGI Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of EphB4 autophosphorylation by cell based assay				Bioorg Med Chem Lett 19: 6991-5 (2009) Article DOI: 10.1016/j.bmcl.2009.10.037 BindingDB Entry DOI: 10.7270/Q2DR2VM3
					More data for this Ligand-Target Pair