BDBM50312191 1-(3-phenoxyphenyl)-3-(3-(8-(pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)urea::CHEMBL1080669

SMILES: O=C(Nc1cccc(Oc2ccccc2)c1)Nc1cccc(c1)-c1cn2ccnc2c(NCc2ccncc2)n1

InChI Key: InChIKey=FCRHJSNRFAAYQD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312191   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ephrin type-B receptor 4 (Homo sapiens (Human))	BDBM50312191 (1-(3-phenoxyphenyl)-3-(3-(8-(pyridin-4-ylmethylami...) Show SMILES O=C(Nc1cccc(Oc2ccccc2)c1)Nc1cccc(c1)-c1cn2ccnc2c(NCc2ccncc2)n1 Show InChI InChI=1S/C31H25N7O2/c39-31(36-25-8-5-11-27(19-25)40-26-9-2-1-3-10-26)35-24-7-4-6-23(18-24)28-21-38-17-16-33-30(38)29(37-28)34-20-22-12-14-32-15-13-22/h1-19,21H,20H2,(H,34,37)(H2,35,36,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
CGI Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of EphB4 autophosphorylation by cell based assay				Bioorg Med Chem Lett 19: 6991-5 (2009) Article DOI: 10.1016/j.bmcl.2009.10.037 BindingDB Entry DOI: 10.7270/Q2DR2VM3
					More data for this Ligand-Target Pair