BDBM50312379 2-(4-((4-(4-chlorophenyl)-5-phenylthiazol-2-yl)methoxy)-2-methylphenoxy)acetic acid::CHEMBL1081602

SMILES: Cc1cc(OCc2nc(c(s2)-c2ccccc2)-c2ccc(Cl)cc2)ccc1OCC(O)=O

InChI Key: InChIKey=TUUHILVKSYAKDX-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312379   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50312379 (2-(4-((4-(4-chlorophenyl)-5-phenylthiazol-2-yl)met...) Show SMILES Cc1cc(OCc2nc(c(s2)-c2ccccc2)-c2ccc(Cl)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C25H20ClNO4S/c1-16-13-20(11-12-21(16)31-15-23(28)29)30-14-22-27-24(17-7-9-19(26)10-8-17)25(32-22)18-5-3-2-4-6-18/h2-13H,14-15H2,1H3,(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50312379 (2-(4-((4-(4-chlorophenyl)-5-phenylthiazol-2-yl)met...) Show SMILES Cc1cc(OCc2nc(c(s2)-c2ccccc2)-c2ccc(Cl)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C25H20ClNO4S/c1-16-13-20(11-12-21(16)31-15-23(28)29)30-14-22-27-24(17-7-9-19(26)10-8-17)25(32-22)18-5-3-2-4-6-18/h2-13H,14-15H2,1H3,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50312379 (2-(4-((4-(4-chlorophenyl)-5-phenylthiazol-2-yl)met...) Show SMILES Cc1cc(OCc2nc(c(s2)-c2ccccc2)-c2ccc(Cl)cc2)ccc1OCC(O)=O Show InChI InChI=1S/C25H20ClNO4S/c1-16-13-20(11-12-21(16)31-15-23(28)29)30-14-22-27-24(17-7-9-19(26)10-8-17)25(32-22)18-5-3-2-4-6-18/h2-13H,14-15H2,1H3,(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair