BDBM50312383 2-(2-methyl-4-((4-(pyridin-3-yl)-5-p-tolylthiazol-2-yl)methoxy)phenoxy)acetic acid::CHEMBL1082116

SMILES: Cc1ccc(cc1)-c1sc(COc2ccc(OCC(O)=O)c(C)c2)nc1-c1cccnc1

InChI Key: InChIKey=ZBWICHRTPIGAMI-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312383   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50312383 (2-(2-methyl-4-((4-(pyridin-3-yl)-5-p-tolylthiazol-...) Show SMILES Cc1ccc(cc1)-c1sc(COc2ccc(OCC(O)=O)c(C)c2)nc1-c1cccnc1 Show InChI InChI=1S/C25H22N2O4S/c1-16-5-7-18(8-6-16)25-24(19-4-3-11-26-13-19)27-22(32-25)14-30-20-9-10-21(17(2)12-20)31-15-23(28)29/h3-13H,14-15H2,1-2H3,(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50312383 (2-(2-methyl-4-((4-(pyridin-3-yl)-5-p-tolylthiazol-...) Show SMILES Cc1ccc(cc1)-c1sc(COc2ccc(OCC(O)=O)c(C)c2)nc1-c1cccnc1 Show InChI InChI=1S/C25H22N2O4S/c1-16-5-7-18(8-6-16)25-24(19-4-3-11-26-13-19)27-22(32-25)14-30-20-9-10-21(17(2)12-20)31-15-23(28)29/h3-13H,14-15H2,1-2H3,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50312383 (2-(2-methyl-4-((4-(pyridin-3-yl)-5-p-tolylthiazol-...) Show SMILES Cc1ccc(cc1)-c1sc(COc2ccc(OCC(O)=O)c(C)c2)nc1-c1cccnc1 Show InChI InChI=1S/C25H22N2O4S/c1-16-5-7-18(8-6-16)25-24(19-4-3-11-26-13-19)27-22(32-25)14-30-20-9-10-21(17(2)12-20)31-15-23(28)29/h3-13H,14-15H2,1-2H3,(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair