BDBM50312423 2-(4-((4-(4-((Piperidin-1-yl)methanone)phenyl)-5-(4-(trifluoromethoxy)phenyl)thiazol-2-yl)methoxy)-2-methylphenoxy)acetic Acid::CHEMBL1075724

SMILES: Cc1cc(OCc2nc(c(s2)-c2ccc(OC(F)(F)F)cc2)-c2ccc(cc2)C(=O)N2CCCCC2)ccc1OCC(O)=O

InChI Key: InChIKey=FTITXPXYYRBMKO-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312423   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50312423 (2-(4-((4-(4-((Piperidin-1-yl)methanone)phenyl)-5-(...) Show SMILES Cc1cc(OCc2nc(c(s2)-c2ccc(OC(F)(F)F)cc2)-c2ccc(cc2)C(=O)N2CCCCC2)ccc1OCC(O)=O Show InChI InChI=1S/C32H29F3N2O6S/c1-20-17-25(13-14-26(20)42-19-28(38)39)41-18-27-36-29(30(44-27)22-9-11-24(12-10-22)43-32(33,34)35)21-5-7-23(8-6-21)31(40)37-15-3-2-4-16-37/h5-14,17H,2-4,15-16,18-19H2,1H3,(H,38,39)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50312423 (2-(4-((4-(4-((Piperidin-1-yl)methanone)phenyl)-5-(...) Show SMILES Cc1cc(OCc2nc(c(s2)-c2ccc(OC(F)(F)F)cc2)-c2ccc(cc2)C(=O)N2CCCCC2)ccc1OCC(O)=O Show InChI InChI=1S/C32H29F3N2O6S/c1-20-17-25(13-14-26(20)42-19-28(38)39)41-18-27-36-29(30(44-27)22-9-11-24(12-10-22)43-32(33,34)35)21-5-7-23(8-6-21)31(40)37-15-3-2-4-16-37/h5-14,17H,2-4,15-16,18-19H2,1H3,(H,38,39)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50312423 (2-(4-((4-(4-((Piperidin-1-yl)methanone)phenyl)-5-(...) Show SMILES Cc1cc(OCc2nc(c(s2)-c2ccc(OC(F)(F)F)cc2)-c2ccc(cc2)C(=O)N2CCCCC2)ccc1OCC(O)=O Show InChI InChI=1S/C32H29F3N2O6S/c1-20-17-25(13-14-26(20)42-19-28(38)39)41-18-27-36-29(30(44-27)22-9-11-24(12-10-22)43-32(33,34)35)21-5-7-23(8-6-21)31(40)37-15-3-2-4-16-37/h5-14,17H,2-4,15-16,18-19H2,1H3,(H,38,39)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.56E+3	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair