null
SMILES: Cc1cc(OCc2nc(c(o2)-c2ccc(OC(F)(F)F)cc2)-c2ccc(cc2)C(=O)N2CCCCC2)ccc1OCC(O)=O
InChI Key: InChIKey=AXPDGDWWEWKWCL-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human)) | BDBM50312429 (2-(4-((4-(4-(Piperidin-1-yl)phenyl)-5-(4-(trifluor...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass... | J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human)) | BDBM50312429 (2-(4-((4-(4-(Piperidin-1-yl)phenyl)-5-(4-(trifluor...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.15E+3 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass... | J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM50312429 (2-(4-((4-(4-(Piperidin-1-yl)phenyl)-5-(4-(trifluor...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL | Assay Description Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass... | J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP | |||||||||||
More data for this Ligand-Target Pair |