BDBM50312459 (4-{2-[4,5-Bis(4-methoxyphenyl)thiazol-2-ylsulfanyl]ethoxy}-2-methylphenoxy)acetic Acid::CHEMBL1081950

SMILES: COc1ccc(cc1)-c1nc(SCCOc2ccc(OCC(O)=O)c(C)c2)sc1-c1ccc(OC)cc1

InChI Key: InChIKey=AXNJWHYVWXFMPK-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312459   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (Homo sapiens (Human))	BDBM50312459 ((4-{2-[4,5-Bis(4-methoxyphenyl)thiazol-2-ylsulfany...) Show SMILES COc1ccc(cc1)-c1nc(SCCOc2ccc(OCC(O)=O)c(C)c2)sc1-c1ccc(OC)cc1 Show InChI InChI=1S/C28H27NO6S2/c1-18-16-23(12-13-24(18)35-17-25(30)31)34-14-15-36-28-29-26(19-4-8-21(32-2)9-5-19)27(37-28)20-6-10-22(33-3)11-7-20/h4-13,16H,14-15,17H2,1-3H3,(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.35E+3	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human))	BDBM50312459 ((4-{2-[4,5-Bis(4-methoxyphenyl)thiazol-2-ylsulfany...) Show SMILES COc1ccc(cc1)-c1nc(SCCOc2ccc(OCC(O)=O)c(C)c2)sc1-c1ccc(OC)cc1 Show InChI InChI=1S/C28H27NO6S2/c1-18-16-23(12-13-24(18)35-17-25(30)31)34-14-15-36-28-29-26(19-4-8-21(32-2)9-5-19)27(37-28)20-6-10-22(33-3)11-7-20/h4-13,16H,14-15,17H2,1-3H3,(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50312459 ((4-{2-[4,5-Bis(4-methoxyphenyl)thiazol-2-ylsulfany...) Show SMILES COc1ccc(cc1)-c1nc(SCCOc2ccc(OCC(O)=O)c(C)c2)sc1-c1ccc(OC)cc1 Show InChI InChI=1S/C28H27NO6S2/c1-18-16-23(12-13-24(18)35-17-25(30)31)34-14-15-36-28-29-26(19-4-8-21(32-2)9-5-19)27(37-28)20-6-10-22(33-3)11-7-20/h4-13,16H,14-15,17H2,1-3H3,(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.66E+3	n/a	n/a	n/a	n/a
The Genomics Institute of the Novartis Research Foundation Curated by ChEMBL					Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass...				J Med Chem 53: 77-105 (2010) Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP
					More data for this Ligand-Target Pair