BDBM50312589 1-(cyclobutylcarbonyl)-4-[(2,4-dichlorophenyl)(phenyl)methyl]piperazine::CHEMBL1076884

SMILES: Clc1ccc(C(N2CCN(CC2)C(=O)C2CCC2)c2ccccc2)c(Cl)c1

InChI Key: InChIKey=NSTSWSVXSSYQCZ-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312589   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50312589 (1-(cyclobutylcarbonyl)-4-[(2,4-dichlorophenyl)(phe...) Show SMILES Clc1ccc(C(N2CCN(CC2)C(=O)C2CCC2)c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C22H24Cl2N2O/c23-18-9-10-19(20(24)15-18)21(16-5-2-1-3-6-16)25-11-13-26(14-12-25)22(27)17-7-4-8-17/h1-3,5-6,9-10,15,17,21H,4,7-8,11-14H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	291	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant cannabinoid CB1 receptor expressed in CHO cells after 3 hrs by liquid scintillation counting				Eur J Med Chem 45: 1133-9 (2010) Article DOI: 10.1016/j.ejmech.2009.12.018 BindingDB Entry DOI: 10.7270/Q2K937P0
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50312589 (1-(cyclobutylcarbonyl)-4-[(2,4-dichlorophenyl)(phe...) Show SMILES Clc1ccc(C(N2CCN(CC2)C(=O)C2CCC2)c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C22H24Cl2N2O/c23-18-9-10-19(20(24)15-18)21(16-5-2-1-3-6-16)25-11-13-26(14-12-25)22(27)17-7-4-8-17/h1-3,5-6,9-10,15,17,21H,4,7-8,11-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant cannabinoid CB2 receptor expressed in CHO cells after 3 hrs by liquid scintillation counting				Eur J Med Chem 45: 1133-9 (2010) Article DOI: 10.1016/j.ejmech.2009.12.018 BindingDB Entry DOI: 10.7270/Q2K937P0
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50312589 (1-(cyclobutylcarbonyl)-4-[(2,4-dichlorophenyl)(phe...) Show SMILES Clc1ccc(C(N2CCN(CC2)C(=O)C2CCC2)c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C22H24Cl2N2O/c23-18-9-10-19(20(24)15-18)21(16-5-2-1-3-6-16)25-11-13-26(14-12-25)22(27)17-7-4-8-17/h1-3,5-6,9-10,15,17,21H,4,7-8,11-14H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB1 receptor expressed in CHO cells coexpressing Galpha15/16 assessed as inhibition of CP55940-induced Ca2+ ...				Eur J Med Chem 45: 1133-9 (2010) Article DOI: 10.1016/j.ejmech.2009.12.018 BindingDB Entry DOI: 10.7270/Q2K937P0
					More data for this Ligand-Target Pair