BDBM50312593 1-[(2,4-dichlorophenyl)(phenyl)methyl]-4-(piperidin-1-ylcarbonyl)piperazine::CHEMBL1089716

SMILES: Clc1ccc(C(N2CCN(CC2)C(=O)N2CCCCC2)c2ccccc2)c(Cl)c1

InChI Key: InChIKey=BHUFAMDEGOUAKE-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50312593   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50312593 (1-[(2,4-dichlorophenyl)(phenyl)methyl]-4-(piperidi...) Show SMILES Clc1ccc(C(N2CCN(CC2)C(=O)N2CCCCC2)c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C23H27Cl2N3O/c24-19-9-10-20(21(25)17-19)22(18-7-3-1-4-8-18)26-13-15-28(16-14-26)23(29)27-11-5-2-6-12-27/h1,3-4,7-10,17,22H,2,5-6,11-16H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant cannabinoid CB1 receptor expressed in CHO cells after 3 hrs by liquid scintillation counting				Eur J Med Chem 45: 1133-9 (2010) Article DOI: 10.1016/j.ejmech.2009.12.018 BindingDB Entry DOI: 10.7270/Q2K937P0
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50312593 (1-[(2,4-dichlorophenyl)(phenyl)methyl]-4-(piperidi...) Show SMILES Clc1ccc(C(N2CCN(CC2)C(=O)N2CCCCC2)c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C23H27Cl2N3O/c24-19-9-10-20(21(25)17-19)22(18-7-3-1-4-8-18)26-13-15-28(16-14-26)23(29)27-11-5-2-6-12-27/h1,3-4,7-10,17,22H,2,5-6,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	987	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]CP-55940 from human recombinant cannabinoid CB2 receptor expressed in CHO cells after 3 hrs by liquid scintillation counting				Eur J Med Chem 45: 1133-9 (2010) Article DOI: 10.1016/j.ejmech.2009.12.018 BindingDB Entry DOI: 10.7270/Q2K937P0
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50312593 (1-[(2,4-dichlorophenyl)(phenyl)methyl]-4-(piperidi...) Show SMILES Clc1ccc(C(N2CCN(CC2)C(=O)N2CCCCC2)c2ccccc2)c(Cl)c1 Show InChI InChI=1S/C23H27Cl2N3O/c24-19-9-10-20(21(25)17-19)22(18-7-3-1-4-8-18)26-13-15-28(16-14-26)23(29)27-11-5-2-6-12-27/h1,3-4,7-10,17,22H,2,5-6,11-16H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Antagonist activity at human cannabinoid CB1 receptor expressed in CHO cells coexpressing Galpha15/16 assessed as inhibition of CP55940-induced Ca2+ ...				Eur J Med Chem 45: 1133-9 (2010) Article DOI: 10.1016/j.ejmech.2009.12.018 BindingDB Entry DOI: 10.7270/Q2K937P0
					More data for this Ligand-Target Pair