BDBM50312712 (S)-4'-cyclohexyl-2'-cyclopentyl-3'-((S)-hydroxy(4-(trifluoromethyl)phenyl)methyl)-6',8'-dihydro-5'H-spiro[cyclobutane-1,7'-quinolin]-5'-ol::CHEMBL1081607

SMILES: O[C@@H](c1ccc(cc1)C(F)(F)F)c1c(nc2CC3(CCC3)C[C@H](O)c2c1C1CCCCC1)C1CCCC1

InChI Key: InChIKey=JZVGGRSWDCYGKK-OUTSHDOLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50312712   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50312712 ((S)-4'-cyclohexyl-2'-cyclopentyl-3'-((S)-hydroxy(4...) Show SMILES O[C@@H](c1ccc(cc1)C(F)(F)F)c1c(nc2CC3(CCC3)C[C@H](O)c2c1C1CCCCC1)C1CCCC1 |r| Show InChI InChI=1S/C31H38F3NO2/c32-31(33,34)22-13-11-21(12-14-22)29(37)27-25(19-7-2-1-3-8-19)26-23(35-28(27)20-9-4-5-10-20)17-30(15-6-16-30)18-24(26)36/h11-14,19-20,24,29,36-37H,1-10,15-18H2/t24-,29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare AG Curated by ChEMBL					Assay Description Inhibition of CETP assessed as cholesterol ester transfer after 4 hrs by microemulsion based fluorescence assay				Bioorg Med Chem Lett 20: 1740-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.071 BindingDB Entry DOI: 10.7270/Q28S4Q1P
					More data for this Ligand-Target Pair